Mycobacterium tuberculosis Genes Needed for Intra-alveolar R…

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Mycobacterium tuberculosis Genes Needed for Intra-alveolar Resuscitation After Airborne Transmission

Preprint 2025 EN Green

(Mtb) must withstand physical and chemical stresses during airborne transmission, including during the desiccation of aerosols small enough to reach pulmonary alveoli in a new host. There, Mtb encounters an antimicrobial pulmonary alveolar lining fluid (ALF) before it is engulfed by macrophages. To study the genes involved in Mtb's ability to survive the transition from desiccated droplet to pulmo…

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15 authors
#AuthorInstitutionsORCID
1 Prabhat Ranjan Singh Corresponding Weill Cornell Medicine (US)
2 Martin Gengenbacher Hackensack Meridian Health (US) Weill Cornell Medicine (US) +1 —
3 Saurabh Mishra Weill Cornell Medicine (US)
4 Adrián Jinich University of California San D… (US)
5 Xiuju Jiang Weill Cornell Medicine (US)
6 Felipe Tsang Weill Cornell Medicine (US) —
7 Melissa Cristaldo Hackensack Meridian Health (US) Hackensack Meridian School of … (US) +1 —
8 Michael DeJesus Weill Cornell Medicine (US) Rockefeller University (US)
9 Kyu Young Rhee Weill Cornell Medicine (US)
10 Robert J. Kaner Weill Cornell Medicine (US)
11 Philip L. Leopold Weill Cornell Medicine (US)
12 Ronald G. Crystal Weill Cornell Medicine (US)
13 Dipak Kathayat Cornell University (US) New York State College of Vete… (US) —
14 Brian C. VanderVen Cornell University (US) New York State College of Vete… (US) —
15 Carl Nathan Weill Cornell Medicine (US)

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