A Pan-H5N1 Multiepitope DNA Vaccine Construct Targeting Some…

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A Pan-H5N1 Multiepitope DNA Vaccine Construct Targeting Some Key Proteins of the Clade 2.3.4.4b Using AI-Assisted Epitope Mapping and Molecular Docking

Article 2025 EN Gold

The presently used vaccines do not offer solid immunity/protection against the currently circulating strains of the H5N1 viruses. We aim to design a pan-H5N1 vaccine that protects birds against the presently circulating clade 2.3.4.4b in chickens. We used AI tools, including epitope mapping, molecular docking, and immune simulation, to design a multiepitope DNA vaccine including the top-ranked B a…

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5 authors
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1 Nithyadevi Duraisamy Long Island University (US)
2 Abid Ullah Shah Long Island University (US)
3 Mohd Yasir Khan Long Island University (US)
4 Mohammed Cherkaoui Long Island University (US) —
5 Maged Gomaa Hemida Corresponding Long Island University (US)

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