Protocol for the HIT-Stroke Trial 2 randomized controlled trial: Moderate-intensity exercise versus high-intensity interval training to determine the optimal training intensity for walking rehabilitation in chronic stroke

Background: Current practice guidelines recommend moderate to vigorous intensity locomotor training to improve walking outcomes in chronic stroke. However, these intensities span a wide range, and the lack of specificity may lead to under-dosing or over-dosing of training intensity. Recent evidence indicates that vigorous intensity locomotor training improves walking outcomes significantly more th…