Single-Cell Multiomics Analysis of Early Wound Response Prog…

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Single-Cell Multiomics Analysis of Early Wound Response Programs in the Mouse Corneal Epithelium

Article 2025 EN Gold

Purpose: Wound healing is crucial for restoring homeostasis in living organisms. Although wound response mechanisms have been studied extensively, the gene regulatory programs involved remain to be elucidated. Here, we used single-cell RNA sequencing (RNA-seq) and ATAC sequencing (ATAC-seq) analysis to profile the regulatory landscape of mouse corneal epithelium in early wound response. Methods: W…

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9

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Authors & Affiliations
9 authors
#AuthorInstitutionsORCID
1 Zhaojing Lu Chinese Academy of Medical Sci… (CN) State Key Laboratory of Ophtha… (CN) +1 —
2 Jin-Guo Ye State Key Laboratory of Ophtha… (CN) Zhongshan Ophthalmic Center, S… (CN) —
3 Jing-Ni Li State Key Laboratory of Ophtha… (CN) Zhongshan Ophthalmic Center, S… (CN) —
4 Jiang-Bo Liang State Key Laboratory of Ophtha… (CN) Zhongshan Ophthalmic Center, S… (CN) —
5 Ming Zhou State Key Laboratory of Ophtha… (CN) Zhongshan Ophthalmic Center, S… (CN)
6 Qiuling Hu State Key Laboratory of Ophtha… (CN) Zhongshan Ophthalmic Center, S… (CN)
7 Qikai Zhang State Key Laboratory of Ophtha… (CN) Zhongshan Ophthalmic Center, S… (CN)
8 Yuheng Lin State Key Laboratory of Ophtha… (CN) Zhongshan Ophthalmic Center, S… (CN)
9 Yingfeng Zheng Corresponding Chinese Academy of Medical Sci… (CN) State Key Laboratory of Ophtha… (CN) +1

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