6569 An Increase, Rather Than Absolute Amount, Of Corticotro…

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  • DOI 10.1210/jendso/bvae163.106
  • OpenAlex ID W4403151721
  • Type Article
  • Language EN
  • Published 01 Oct 2024
  • Volume 8 (Supplement_1)
  • Source Journal of the Endocrine Society
  • Publisher Endocrine Society
  • Countries 2
  • Institutions 4
  • Added 06 Oct 2024
  • Updated 29 Oct 2026
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6569 An Increase, Rather Than Absolute Amount, Of Corticotropin-Releasing Hormone (Crh) Drives Mouse Anxiety-Like Behavior

Article 2024 EN Gold

Abstract Disclosure: H.R. Friedman: None. L. Gaston: None. L. Chan: None. J.A. Majzoub: None. Approximately 300 million people have an anxiety disorder. We previously found that anxiety-like behavior (AB) is decreased in mice which lack hypothalamic (HT) Crh (1), so we hypothesized that increased HT Crh, due to primary adrenal insufficiency (PAI), would induce increased AB. To evaluate this, we co…

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UN Sustainable Development Goals
1 SDGs
Authors & Affiliations
4 authors
#AuthorInstitutionsORCID
1 Hannah Rose Friedman Boston Children's Hospital (US) Harvard University (US) —
2 Lindsey S. Gaston Boston Children's Hospital (US) Harvard University (US)
3 Li F. Chan Queen Mary University of Londo… (GB) William Harvey Research Instit… (GB)
4 Joseph A. Majzoub Boston Children's Hospital (US) Harvard University (US)

Data: OpenAlex