Three families of CD4-induced antibodies are associated with…
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- DOI 10.1128/jvi.00960-24
- PMID https://pubmed.ncbi.nlm.nih.gov/38883797
- OpenAlex ID W4402229400
- Type Article
- Language EN
- Published 04 Sep 2024
- Volume 98 (10)
- Pages e0096024
- Source Journal of Virology
- Publisher American Society for Microbiology
- FWCI 2.64
- Countries 2
- Institutions 4
- Added 10 Oct 2025
- Updated 16 Oct 2026
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Three families of CD4-induced antibodies are associated with the capacity of plasma from people living with HIV to mediate ADCC in the presence of CD4-mimetics
Article 2024 EN Green
CD4-mimetics (CD4mcs) are small molecule compounds that mimic the interaction of the CD4 receptor with HIV-1 envelope glycoproteins (Env). Env from primary viruses normally samples a "closed" conformation that occludes epitopes recognized by CD4-induced (CD4i) non-neutralizing antibodies (nnAbs). CD4mcs induce conformational changes on Env resulting in the exposure of these otherwise inaccessible…
13
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51
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18
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2.64
FWCI
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1 SDGsAuthors & Affiliations
18 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Alexandra Tauzin | Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA) | |
| 2 | Lorie Marchitto | Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA) | |
| 3 | Étienne Bélanger | Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA) | — |
| 4 | Mehdi Benlarbi | Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA) | |
| 5 | Guillaume Beaudoin-Bussières | Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA) | |
| 6 | Jérémie Prévost | Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA) | |
| 7 | Derek Yang | University of Pennsylvania (US) | — |
| 8 | Ta-Jung Chiu | University of Pennsylvania (US) | |
| 9 | Hung-Ching Chen | University of Pennsylvania (US) | |
| 10 | Catherine Bourassa | Centre Hospitalier de l’Univer… (CA) | |
| 11 | Halima Medjahed | Centre Hospitalier de l’Univer… (CA) | — |
| 12 | Marek Korzeniowski | Uniformed Services University … (US) | |
| 13 | Suneetha Gottumukkala | Uniformed Services University … (US) | — |
| 14 | William David Tolbert | Uniformed Services University … (US) | |
| 15 | Jonathan Richard | Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA) | |
| 16 | Amos B. Smith | University of Pennsylvania (US) | |
| 17 | Marzena Pazgier | Uniformed Services University … (US) | |
| 18 | Andrés Finzi Corresponding | Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA) |
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