NTB-A and 2B4 Natural Killer Cell Receptors Modulate the Cap…

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  • DOI 10.3390/v16071167
  • PMID https://pubmed.ncbi.nlm.nih.gov/39066329
  • OpenAlex ID W4400886163
  • Type Article
  • Language EN
  • Published 20 Jul 2024
  • Volume 16 (7)
  • Pages 1167
  • Source Viruses
  • Publisher Multidisciplinary Digital Publishin…
  • FWCI 0.14
  • Countries 2
  • Institutions 3
  • Added 10 Oct 2025
  • Updated 20 Oct 2026
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NTB-A and 2B4 Natural Killer Cell Receptors Modulate the Capacity of a Cocktail of Non-Neutralizing Antibodies and a Small CD4-Mimetic to Eliminate HIV-1-Infected Cells by Antibody-Dependent Cellular Cytotoxicity

Article 2024 EN Gold

Natural Killer (NK) cells have the potential to eliminate HIV-1-infected cells by antibody-dependent cellular cytotoxicity (ADCC). NK cell activation is tightly regulated by the engagement of its inhibitory and activating receptors. The activating receptor CD16 drives ADCC upon binding to the Fc portion of antibodies; NK cell activation is further sustained by the co-engagement of activating recep…

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15 authors
#AuthorInstitutionsORCID
1 Lorie Marchitto Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA)
2 Alexandra Tauzin Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA)
3 Mehdi Benlarbi Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA)
4 Guillaume Beaudoin-Bussières Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA)
5 Katrina Dionne Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA) —
6 Étienne Bélanger Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA) —
7 Debashree Chatterjee Centre Hospitalier de l’Univer… (CA)
8 Catherine Bourassa Centre Hospitalier de l’Univer… (CA)
9 Halima Medjahed Centre Hospitalier de l’Univer… (CA) —
10 Derek Yang University of Pennsylvania (US) —
11 Ta-Jung Chiu University of Pennsylvania (US)
12 Hung-Ching Chen University of Pennsylvania (US)
13 Amos B. Smith University of Pennsylvania (US)
14 Jonathan Richard Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA)
15 Andrés Finzi Corresponding Centre Hospitalier de l’Univer… (CA) Université de Montréal (CA)
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