PARP inhibitors combined with radiotherapy: are we ready?
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46
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- DOI 10.3389/fphar.2023.1234973
- PMID https://pubmed.ncbi.nlm.nih.gov/37954854
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/10637512
- OpenAlex ID W4388015584
- Type Review
- Language EN
- Published 26 Oct 2023
- Volume 14
- Pages 1234973
- Source Frontiers in Pharmacology
- Publisher Frontiers Media
- FWCI 1.49
- Countries 1
- Institutions 1
- Added 01 Nov 2023
- Updated 29 Oct 2026
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PARP inhibitors combined with radiotherapy: are we ready?
Review 2023 EN Gold
PARP was an enzyme found in the nucleus of eukaryotic cells that played a crucial role in repairing damaged DNA. Recently, PARP inhibitors have demonstrated great potential in cancer treatment. Thus, the FDA has approved several small-molecule PARP inhibitors for cancer maintenance therapy. The combination of PARP inhibitors and radiotherapy relies on synthetic lethality, taking advantage of the f…
46
Citations
95
References
7
Authors
1.49
FWCI
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
7 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Chen Sun | Second Affiliated Hospital of … (CN) | |
| 2 | Alan Chu | Second Affiliated Hospital of … (CN) | |
| 3 | Rui Song | Second Affiliated Hospital of … (CN) | |
| 4 | Shijia Liu | Second Affiliated Hospital of … (CN) | |
| 5 | Ting Chai | Second Affiliated Hospital of … (CN) | — |
| 6 | Xin Wang | Second Affiliated Hospital of … (CN) | |
| 7 | Zongwen Liu | Second Affiliated Hospital of … (CN) | — |
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