Quantification of levetiracetam in plasma and urine and its …
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- DOI 10.4155/bio-2022-0230
- PMID https://pubmed.ncbi.nlm.nih.gov/36927087
- OpenAlex ID W4327678685
- Type Article
- Language EN
- Published 01 Jan 2023
- Volume 15 (1)
- Pages 31–42
- Source Bioanalysis
- Publisher Future Science Ltd
- FWCI 0.24
- Countries 2
- Institutions 4
- Added 10 Oct 2025
- Updated 17 Oct 2026
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Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients
Article 2023 EN Hybrid
Background: Levetiracetam is an antiepileptic drug used to prevent or treat seizure in patients with severe traumatic brain injury. This study aimed to develop and validate methodology suitable for measuring levetiracetam concentrations in human plasma and urine. Methods: Plasma or urine (10 μl) samples were spiked with [2H6]-levetiracetam and processed using an acetonitrile precipitation. ESI–LC–…
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1 SDGsAuthors & Affiliations
8 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Santosh Kumar Sreevatsav Adiraju | The University of Queensland (AU) | |
| 2 | Chandra Datta Sumi | The University of Queensland (AU) | |
| 3 | Saurabh Pandey | The University of Queensland (AU) | |
| 4 | Menino Osbert Cotta | The University of Queensland (AU) | |
| 5 | Jason Alexander Roberts | The University of Queensland (AU) Université de Montpellier (FR) +2 | |
| 6 | Jeffrey Lipman | The University of Queensland (AU) Université de Montpellier (FR) +2 | |
| 7 | Steven C. Wallis | The University of Queensland (AU) | |
| 8 | Suzanne L. Parker | The University of Queensland (AU) |
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