Dihydroxy-Metabolites of Dihomo-γ-linolenic Acid Drive Ferro…

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Dihydroxy-Metabolites of Dihomo-γ-linolenic Acid Drive Ferroptosis-Mediated Neurodegeneration

Article 2023 EN Diamond

Even after decades of research, the mechanism of neurodegeneration remains understudied, hindering the discovery of effective treatments for neurodegenerative diseases. Recent reports suggest that ferroptosis could be a novel therapeutic target for neurodegenerative diseases. While polyunsaturated fatty acid (PUFA) plays an important role in neurodegeneration and ferroptosis, how PUFAs may trigger…

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12 authors
#AuthorInstitutionsORCID
1 Morteza Sarparast Michigan State University (US) —
2 Elham Pourmand Michigan State University (US) —
3 Jennifer Hinman Michigan State University (US)
4 Derek Vonarx Michigan State University (US) —
5 Tommy Reason Michigan State University (US) —
6 Fan Zhang Michigan State University (US)
7 Shreya Paithankar Michigan State University (US)
8 Bin Chen Michigan State University (US)
9 Babak Borhan Michigan State University (US)
10 Jennifer L. Watts Washington State University (US)
11 Jamie K. Alan Corresponding Michigan State University (US)
12 Kin Sing Stephen Lee Corresponding Michigan State University (US)

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