Local production of corticotropin-releasing hormone in prefr…

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Local production of corticotropin-releasing hormone in prefrontal cortex modulates male-specific novelty exploration

Article 2022 EN Hybrid

Neuromodulatory substances can be released from distal afferents for communication between brain structures or produced locally to modulate neighboring circuit elements. Corticotropin-releasing hormone (CRH) from long-range neurons in the hypothalamus projecting to the medial prefrontal cortex (mPFC) has been shown to induce anxiety-like behaviors. However, the role of CRH produced in the mPFC has…

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4 authors
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1 Michael H. Riad Howard Hughes Medical Institut… (US) Rockefeller University (US) —
2 Kwanghoon Park Howard Hughes Medical Institut… (US) Rockefeller University (US)
3 Inés Ibáñez-Tallon Howard Hughes Medical Institut… (US) Rockefeller University (US)
4 Nathaniel Heintz Corresponding Howard Hughes Medical Institut… (US) Rockefeller University (US)

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