A combination vaccine against SARS-CoV-2 and H1N1 influenza …

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A combination vaccine against SARS-CoV-2 and H1N1 influenza based on receptor binding domain trimerized by six-helix bundle fusion core

Article 2022 EN Gold

BACKGROUND: Increasing severe morbidity and mortality by simultaneous or sequential infections with SARS-CoV-2 and influenza A viruses (IAV), especially in the elderly and obese patients, highlight the urgency of developing a combination vaccine against COVID-19 and influenza. METHODS: Self-assembling SARS-CoV-2 RBD-trimer and Influenza H1N1 HA1-trimer antigens were constructed, upon the stable fu…

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11 authors
#AuthorInstitutionsORCID
1 Rui Shi Chinese Academy of Sciences (CN) Institute of Microbiology (CN)
2 Jiawei Zeng Chinese Academy of Sciences (CN) Institute of Microbiology (CN) +1 —
3 Ling Xu Kunming Institute of Zoology (CN) Chinese Academy of Sciences (CN)
4 Fengze Wang Chinese Academy of Sciences (CN) Institute of Microbiology (CN) +1
5 Xiaomin Duan Chinese Academy of Sciences (CN) Institute of Microbiology (CN) +1 —
6 Yue Wang Chinese Academy of Sciences (CN) Institute of Microbiology (CN) +1
7 Zheng Wu Anhui University (CN) Chinese Academy of Sciences (CN) +1
8 Dandan Yu Kunming Institute of Zoology (CN) Chinese Academy of Sciences (CN)
9 Qingrui Huang Corresponding Chinese Academy of Sciences (CN) Institute of Microbiology (CN)
10 Yong‐Gang Yao Corresponding Kunming Institute of Zoology (CN) Chinese Academy of Sciences (CN) +1
11 Jinghua Yan Corresponding Chinese Academy of Sciences (CN) Institute of Microbiology (CN) +1

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