Spermatogenesis and Ovulation (Gonadotropin Control)

After stimulation by GnRH, the gonadotropes also secrete FSH into the circulation. This glycoprotein hormone binds to specific receptors on Sertoli cells of the testes, stimulating production of androgen-binding protein (ABP). FSH is necessary for the initiation of spermatogenesis. However, full maturation of spermatozoa also appears to require testosterone. Indeed, the major action of FSH on sper…