The Fragile X Syndrome‐Related Protein, FMRP, Modulates Innate Immune Gene Expression in Macrophages

Fragile X mental retardation protein (FMRP) is an RNA‐binding protein with a wide range of functions, including mRNA translation, mRNA transport, and mitochondrial organization. Loss of FMRP due to silencing of the FRM1 gene is associated with intellectual disability and has been implicated in viral pathogenesis and cancer risk. However, the contribution of FMRP to innate immunity in response to b…