Vitamin D activates FBP1 to block the Warburg effect and mod…

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Vitamin D activates FBP1 to block the Warburg effect and modulate blast metabolism in acute myeloid leukemia

Article 2022 EN Gold

Acute myeloid leukemia (AML) has the lowest survival rate among the leukemias. Targeting intracellular metabolism and energy production in leukemic cells can be a promising therapeutic strategy for AML. Recently, we presented the successful use of vitamin D (1,25VD3) gene therapy to treat AML mouse models in vivo. In this study, recognizing the importance of 1,25VD3 as one of only 2 molecules (alo…

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8 authors
#AuthorInstitutionsORCID
1 Yi Xu Corresponding Loma Linda University Medical … (US) Loma Linda University (US)
2 Christopher Hino Loma Linda University Medical … (US) Loma Linda University (US)
3 David J. Baylink Loma Linda University (US)
4 Jeffrey Xiao Loma Linda University (US)
5 Mark Evan Reeves Loma Linda University Medical … (US) Loma Linda University (US)
6 Jiang F. Zhong Loma Linda University (US)
7 Saied Mirshahidi Loma Linda University Medical … (US) Loma Linda University (US)
8 Huynh Le Cao Loma Linda University Medical … (US) Loma Linda University (US) —

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