Antigen-based multiplex strategies to discriminate SARS-CoV-…

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Antigen-based multiplex strategies to discriminate SARS-CoV-2 natural and vaccine induced immunity from seasonal human coronavirus humoral responses

Preprint 2021 EN Green

ABSTRACT Sensitive and specific SARS-CoV-2 antibody assays remain critical for community and hospital-based SARS-CoV-2 sero-surveillance. With the rollout of SARS-CoV-2 vaccines, such assays must be able to distinguish vaccine from natural immunity to SARS-CoV-2 and related human coronaviruses. Here, we developed and implemented multiplex microsphere-based immunoassay strategies for COVD-19 antibo…

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29 authors
#AuthorInstitutionsORCID
1 Eric D. Laing Corresponding Uniformed Services University … (US)
2 Spencer L. Sterling Henry M. Jackson Foundation (US) Uniformed Services University … (US)
3 Stephanie A Richard Henry M. Jackson Foundation (US) Uniformed Services University … (US)
4 Nusrat J Epsi Henry M. Jackson Foundation (US) Uniformed Services University … (US)
5 Si’Ana A. Coggins Henry M. Jackson Foundation (US) Uniformed Services University … (US)
6 Emily C Samuels Henry M. Jackson Foundation (US) Uniformed Services University … (US)
7 Shreshta Phogat Henry M. Jackson Foundation (US) Uniformed Services University … (US) —
8 Lianying Yan Henry M. Jackson Foundation (US) Uniformed Services University … (US)
9 Nicole Moreno Henry M. Jackson Foundation (US) Uniformed Services University … (US) —
10 Christian L. Coles Henry M. Jackson Foundation (US) Uniformed Services University … (US)
11 Matthew R. Drew Frederick National Laboratory … (US) National Cancer Institute (US)
12 Jennifer L. Mehalko Frederick National Laboratory … (US) National Cancer Institute (US) —
13 Caroline E. English Henry M. Jackson Foundation (US) Uniformed Services University … (US) —
14 Scott Merritt Henry M. Jackson Foundation (US) Brooke Army Medical Center (US) +2 —
15 Katrin Mende Henry M. Jackson Foundation (US) Brooke Army Medical Center (US) +2 —
16 Vincent Jacobus Munster National Institutes of Health (US) National Institute of Allergy … (US) +1
17 Emmie de Wit National Institutes of Health (US) National Institute of Allergy … (US) +1
18 Kevin K. Chung Uniformed Services University … (US)
19 Eugene V. Millar Henry M. Jackson Foundation (US) Uniformed Services University … (US)
20 David R. Tribble Uniformed Services University … (US)
21 Mark P. Simons Uniformed Services University … (US)
22 Simon D. Pollett Henry M. Jackson Foundation (US) Uniformed Services University … (US)
23 Brian K. Agan Henry M. Jackson Foundation (US) Uniformed Services University … (US)
24 Dominic Esposito Frederick National Laboratory … (US) National Cancer Institute (US)
25 Charlotte Anne Lanteri Henry M. Jackson Foundation (US) —
26 Guy Travis Clifton Brooke Army Medical Center (US) Joint Base San Antonio (US)
27 Edward E.S. Mitre Uniformed Services University … (US)
28 Timothy H. Burgess Henry M. Jackson Foundation (US)
29 Christopher C. Broder Corresponding Uniformed Services University … (US)

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