Role of hypoxia-inducible factor-1a in ischemia/reperfusion …

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  • DOI 10.3760/cma.j.issn.1673-4203.2019.09.015
  • OpenAlex ID W3029528530
  • Type Article
  • Language EN
  • Published 15 Sep 2019
  • Volume 46 (9)
  • Pages 634–639
  • Source International Journal of Surgery
  • Publisher Wolters Kluwer
  • Countries 1
  • Institutions 2
  • Added 10 Oct 2025
  • Updated 12 Oct 2026
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Role of hypoxia-inducible factor-1a in ischemia/reperfusion injury of donor kidney during kidney transplantation

Article 2019 EN

In the process of kidney acquisition and transplantation, the donor kidney undergoes hypoxia, ischemia and reperfusion, which inevitably leads to ischemia/reperfusion (I/R) injury of the donor kidney. Hypoxia-inducible factor-1α(HIF-1α) is a ubiquitous oxygen-sensitive transcription factor. It can be activated rapidly during I/R injury. Then preventing and reducing the I/R injury of donor kidney d…

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4 authors
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1 Yuanming Han — —
2 Shuang Guo Lanzhou University Second Hosp… (CN) Lanzhou University (CN)
3 Xuanpeng Li Lanzhou University Second Hosp… (CN) Lanzhou University (CN)
4 Yang Li Lanzhou University Second Hosp… (CN) Lanzhou University (CN)
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