[Side Effects of Acetaminophen and their Management].

Acetaminophen, a para-aminohenol derivative, was first clinically used in 1893. In 1980 s, the relevance of aspirin for Reye's syndrome became a problem, then acetaminophen came into use for various kinds of cases such as children, pregnant women and the elderly for pain management or alleviation of fever. However, because acetaminophen has a very weak COX-1 and COX-2 inhibitory effect it has weak…