ANXA2 promotes esophageal cancer progression by activating M…

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ANXA2 promotes esophageal cancer progression by activating MYC-HIF1A-VEGF axis

Article 2018 EN Gold

BACKGROUND: ANXA2 (Annexin A2) is a pleiotropic calcium-dependent phospholipid binding protein that is abnormally expressed in various cancers. We previously found that ANXA2 is upregulated in esophageal squamous cell carcinoma (ESCC). This study was designed to investigate the functional significance of ANXA2 dysregulation and underlying mechanism in ESCC. METHODS: Proliferation, migration, invas…

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11 authors
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1 Sai Ma Chinese Academy of Medical Sci… (CN) State Key Laboratory of Molecu… (CN)
2 Chenchen Lü Bengbu Medical College (CN) Chinese Academy of Medical Sci… (CN) +1
3 Li-Yan Yang Chinese Academy of Medical Sci… (CN) State Key Laboratory of Molecu… (CN) —
4 Juan-Juan Wang Chinese Academy of Medical Sci… (CN) State Key Laboratory of Molecu… (CN) —
5 Boshi Wang Shanghai Jiao Tong University (CN) Renji Hospital (CN) +2
6 Hong‐Qing Cai Chinese Academy of Medical Sci… (CN) State Key Laboratory of Molecu… (CN)
7 Jia‐Jie Hao Chinese Academy of Medical Sci… (CN) State Key Laboratory of Molecu… (CN) —
8 Xin Xu Chinese Academy of Medical Sci… (CN) State Key Laboratory of Molecu… (CN)
9 Yan Cai Chinese Academy of Medical Sci… (CN) State Key Laboratory of Molecu… (CN) —
10 Yu Zhang Corresponding Chinese Academy of Medical Sci… (CN) State Key Laboratory of Molecu… (CN)
11 Ming‐Rong Wang Corresponding Chinese Academy of Medical Sci… (CN) State Key Laboratory of Molecu… (CN)
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