Space microgravity drives transdifferentiation of human bone…

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Space microgravity drives transdifferentiation of human bone marrow‐derived mesenchymal stem cells from osteogenesis to adipogenesis

Article 2018 EN

Bone formation is linked with osteogenic differentiation of mesenchymal stem cells (MSCs) in the bone marrow. Microgravity in spaceflight is known to reduce bone formation. In this study, we used a real microgravity environment of the SJ-10 Recoverable Scientific Satellite to examine the effects of space microgravity on the osteogenic differentiation of human bone marrow-derived mesenchymal stem c…

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13 authors
#AuthorInstitutionsORCID
1 Cui Zhang Zhejiang University (CN)
2 Liang Li Zhejiang University (CN)
3 Yuanda Jiang Chinese Academy of Sciences (CN) National Space Science Center (CN) —
4 Cuicui Wang Zhejiang University (CN)
5 Baoming Geng Chinese Academy of Sciences (CN) National Space Science Center (CN) —
6 Yanqiu Wang Chinese Academy of Sciences (CN) National Space Science Center (CN)
7 Jianling Chen Zhejiang University (CN)
8 Fei Liu —
9 Peng Qiu Chinese Academy of Sciences (CN) National Space Science Center (CN) —
10 Guangjie Zhai Chinese Academy of Sciences (CN) National Space Science Center (CN) —
11 Ping Chen Emory University (US) —
12 Renfu Quan Corresponding —
13 Jinfu Wang Corresponding Zhejiang University (CN)

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