Origin and Quantitative Control of Sertoli Cells

Sertoli cell is the"nurse"in testes that regulates germ cell proliferation and differentiation. One Sertoli cell supports a certain number of germ cells during these processes. Thus, it is the determinant of male reproductive capability. Sertoli cells originate from the primitive gonads during embryonic stage and their proliferations continue throughout the pre-pubertal stage. The proliferation an…