Implementation of pattern‐mixture models in randomized clini…

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  • DOI 10.1002/pst.1780
  • PMID https://pubmed.ncbi.nlm.nih.gov/27658505
  • OpenAlex ID W2532125112
  • Type Article
  • Language EN
  • Published 23 Sep 2016
  • Volume 15 (6)
  • Pages 494–506
  • Source Pharmaceutical Statistics
  • Publisher Wiley
  • Countries 2
  • Institutions 3
  • Added 28 Oct 2016
  • Updated 14 Oct 2026
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Implementation of pattern‐mixture models in randomized clinical trials

Article 2016 EN Green

Modern analysis of incomplete longitudinal outcomes involves formulating assumptions about the missingness mechanisms and then using a statistical method that produces valid inferences under this assumption. In this manuscript, we define missingness strategies for analyzing randomized clinical trials (RCTs) based on plausible clinical scenarios. Penalties for dropout are also introduced in an atte…

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2 authors
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1 Pierre Bunouf Corresponding Pierre Fabre (France) (FR)
2 Geert Molenberghs Hasselt University (BE) KU Leuven (BE)
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