Smad4 controls bone homeostasis through regulation of osteob…
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- DOI 10.1038/emm.2016.75
- PMID https://pubmed.ncbi.nlm.nih.gov/27585718
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/5050296
- OpenAlex ID W2507544731
- Type Article
- Language EN
- Published 02 Sep 2016
- Volume 48 (9)
- Pages e256
- Source Experimental & Molecular Medicine
- Publisher Springer Nature
- FWCI 2.25
- Countries 1
- Institutions 2
- Added 16 Sep 2016
- Updated 28 Oct 2026
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Smad4 controls bone homeostasis through regulation of osteoblast/osteocyte viability
Article 2016 EN Gold
Regulation of osteoblast and osteocyte viability is essential for bone homeostasis. Smad4, a major transducer of bone morphogenetic protein and transforming growth factor-β signaling pathways, regulates apoptosis in various cell types through a mitochondrial pathway. However, it remains poorly understood whether Smad4 is necessary for the regulation of osteoblast and osteocyte viability. In this s…
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1 SDGsAuthors & Affiliations
7 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Young Jae Moon | Jeonbuk National University (KR) | |
| 2 | Chi-Young Yun | Jeonbuk National University (KR) | — |
| 3 | HwaJung Choi | Jeonbuk National University (KR) | |
| 4 | Sun‐O Ka | Jeonbuk National University (KR) | — |
| 5 | Jung Ryul Kim | Jeonbuk National University Ho… (KR) Jeonbuk National University (KR) | |
| 6 | Byung‐Hyun Park | Jeonbuk National University (KR) | |
| 7 | Eui‐Sic Cho Corresponding | Jeonbuk National University (KR) |
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