Cortistatin Is a Key Factor Regulating the Sex-Dependent Res…

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  • DOI 10.1210/en.2016-1195
  • PMID https://pubmed.ncbi.nlm.nih.gov/27175972
  • OpenAlex ID W2391409986
  • Type Article
  • Language EN
  • Published 13 May 2016
  • Volume 157 (7)
  • Pages 2810–2823
  • Source Endocrinology
  • Publisher Oxford University Press
  • FWCI 2.02
  • Countries 2
  • Institutions 9
  • Added 10 Oct 2025
  • Updated 16 Oct 2026
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Cortistatin Is a Key Factor Regulating the Sex-Dependent Response of the GH and Stress Axes to Fasting in Mice

Article 2016 EN Green

Cortistatin (CORT) shares high structural and functional similarities with somatostatin (SST) but displays unique sex-dependent pituitary actions. Indeed, although female CORT-knockout (CORT-KO) mice exhibit enhanced GH expression/secretion, Proopiomelanocortin expression, and circulating ACTH/corticosterone/ghrelin levels, male CORT-KO mice only display increased plasma GH/corticosterone levels.…

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6 authors
#AuthorInstitutionsORCID
1 José Córdoba‐Chacón Spanish Biomedical Research Ce… (ES) University of Illinois Chicago (US) +5
2 Manuel David Gahete Spanish Biomedical Research Ce… (ES) Instituto Maimónides de Invest… (ES) +3
3 Ana I. Pozo-Salas Spanish Biomedical Research Ce… (ES) Instituto Maimónides de Invest… (ES) +3 —
4 Luı́s de Lecea Stanford Medicine (US) Stanford University (US)
5 Justo Pastor Castano Spanish Biomedical Research Ce… (ES) Instituto Maimónides de Invest… (ES) +3
6 Raul Miguel Luque Corresponding Spanish Biomedical Research Ce… (ES) Instituto Maimónides de Invest… (ES) +3
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