Mechanisms of Cardioprotection of Myocardial Ischemic Preconditioning

Ischemic preconditioning (IPC) is a phenomenon during which myocardium, subjected to brief episodes of ischemia followed by reperfusion, tolerates better the subsequent, more prolonged episode of this ischemia followed by reperfusion. Its signal transduction pathways involve trigger-mediators-effectors. Through effectors, IPC protects myocardium by reperfusion.