Interleukin-2 Augmentation of Interleukin-1 and Prostaglandi…

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1989
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  • DOI 10.1002/jlb.45.5.474
  • PMID https://pubmed.ncbi.nlm.nih.gov/2785152
  • OpenAlex ID W2342704014
  • Type Article
  • Language EN
  • Published 01 May 1989
  • Volume 45 (5)
  • Pages 474–477
  • Source Journal of Leukocyte Biology
  • Publisher Oxford University Press
  • FWCI 0.82
  • Countries 1
  • Institutions 3
  • Added 24 Jun 2016
  • Updated 27 Oct 2026
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Interleukin-2 Augmentation of Interleukin-1 and Prostaglandin E2 Production

Article 1989 EN

Some of the major side effects of interleukin-2 (IL-2) therapy in the treatment of malignancies may be related to increased interleukin-1 (IL-1) and/or prostaglandin E2 (PGE2) production. We examined the effect of recombinant (rIL-2) on the in vitro production of IL-1 beta and PGE2 by unstimulated and LPS-activated human blood mononuclear cells (PBMC). We also compared the effect of rIL-2 on IL-1…

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1 Arabella B. Tilden Corresponding University of Alabama at Birmi… (US) Birmingham VA Medical Center (US) —
2 Nancy E. Dunlap University of Alabama at Birmi… (US) UAB Medicine (US) —
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