Rapid GC Method for Quantitation of Nifedipine in Serum Usin…
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- DOI 10.1093/chromsci/21.9.415
- PMID https://pubmed.ncbi.nlm.nih.gov/6630401
- OpenAlex ID W2321903790
- Type Article
- Language EN
- Published 01 Sep 1983
- Volume 21 (9)
- Pages 415–419
- Source Journal of Chromatographic Science
- Publisher Oxford University Press
- FWCI 8.38
- Countries 1
- Institutions 3
- Added 10 Oct 2025
- Updated 21 Aug 2026
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Rapid GC Method for Quantitation of Nifedipine in Serum Using Electron Capture Detection
Article 1983 EN
For studying the pharmacokinetics of nifedipine after single doses, a rapid, specific, reliable gas chromatographic assay procedure for nifedipine in serum is developed. Using a single-step solvent extraction or a bonded-phase column extraction and electron capture detection, an assay sensitivity of 10 to 25 ng/ml can be achieved using 0.25 ml of serum. The assay quantitates intact nifedipine and…
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8.38
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4 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Lawrence J. Lesko Corresponding | University of Maryland, Baltim… (US) | |
| 2 | A. K. Miller | University of Maryland, Baltim… (US) | — |
| 3 | Russell L. Yeager | National Institutes of Health (US) National Institutes of Health … (US) | — |
| 4 | Dulal C. Chatterji | National Institutes of Health (US) National Institutes of Health … (US) | — |
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