The Third International Consensus Definitions for Sepsis and…
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- DOI 10.1001/jama.2016.0287
- PMID https://pubmed.ncbi.nlm.nih.gov/26903338
- OpenAlex ID W2280404143
- Type Article
- Language EN
- Published 22 Feb 2016
- Volume 315 (8)
- Pages 801
- Source JAMA
- Publisher American Medical Association
- FWCI 1,538.91
- Countries 8
- Institutions 23
- Added 10 Oct 2025
- Updated 22 Oct 2026
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The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
Article 2016 EN Bronze
IMPORTANCE: Definitions of sepsis and septic shock were last revised in 2001. Considerable advances have since been made into the pathobiology (changes in organ function, morphology, cell biology, biochemistry, immunology, and circulation), management, and epidemiology of sepsis, suggesting the need for reexamination. OBJECTIVE: To evaluate and, as needed, update definitions for sepsis and septic…
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19 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Mervyn Singer | University College London (GB) | |
| 2 | Clifford Scott Deutschman Corresponding | Feinstein Institute for Medica… (US) Hofstra University (US) | |
| 3 | Christopher W. Seymour | University of Pittsburgh (US) | |
| 4 | Manu Shankar‐Hari | Guy's and St Thomas' NHS Found… (GB) | |
| 5 | Djillali Annane | Université de Versailles Saint… (FR) | |
| 6 | Michael W Bauer | Jena University Hospital (DE) Center for Sepsis Control and … (DE) | |
| 7 | Rinaldo Bellomo | Austin Hospital (AU) Monash University (AU) | |
| 8 | Gordon R. Bernard | Vanderbilt University (US) | |
| 9 | Jean‐Daniel Chiche | Hôpital Cochin (FR) Institut Cochin (FR) | |
| 10 | Craig M. Coopersmith | Emory University (US) | |
| 11 | Richard S. Hotchkiss | Washington University in St. L… (US) | |
| 12 | Mitchell M. Levy | Brown University (US) | |
| 13 | John C. Marshall | University of Toronto (CA) | |
| 14 | Greg S. Martin | Grady Memorial Hospital (US) Emory University (US) | |
| 15 | Steven M. Opal | Brown University (US) | — |
| 16 | Gordon David Rubenfeld | Sunnybrook Health Science Cent… (CA) University of Toronto (CA) | — |
| 17 | Tom van der Poll | Amsterdam UMC Location Univers… (NL) | |
| 18 | Jean‐Louis Vincent | Erasmus Hospital (BE) | |
| 19 | Derek C. Angus | University of Pittsburgh (US) UPMC Health System (US) +1 |
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