Efficient Preparation of Site-Specific Antibody–Drug Conjuga…
Established
47
Citations54
Refs2015
Year
Search Works
Work Details
- DOI 10.1021/acs.bioconjchem.5b00558
- PMID https://pubmed.ncbi.nlm.nih.gov/26588668
- OpenAlex ID W2258784252
- Type Article
- Language EN
- Published 20 Nov 2015
- Volume 26 (12)
- Pages 2554–2562
- Source Bioconjugate Chemistry
- Publisher American Chemical Society
- FWCI 2.71
- Countries 1
- Institutions 1
- Added 10 Oct 2025
- Updated 13 Oct 2026
External Links
MENU
0
Efficient Preparation of Site-Specific Antibody–Drug Conjugates Using Phosphopantetheinyl Transferases
Article 2015 EN
Post-translational modification catalyzed by phosphopantetheinyl transferases (PPTases) has previously been used to site-specifically label proteins with structurally diverse molecules. PPTase catalysis results in covalent modification of a serine residue in acyl/peptidyl carrier proteins and their surrogate substrates which are typically fused to the N- or C-terminus. To test the utility of PPTas…
47
Citations
54
References
20
Authors
2.71
FWCI
Citations by Year
Last 10 yearsTopics
Keywords
UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
20 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Jan Grünewald Corresponding | Genomics Institute of the Nova… (US) | |
| 2 | Heath E. Klock | Genomics Institute of the Nova… (US) | — |
| 3 | Susan E. Cellitti | Genomics Institute of the Nova… (US) | |
| 4 | Badry D. Bursulaya | Genomics Institute of the Nova… (US) | — |
| 5 | Daniel McMullan | Genomics Institute of the Nova… (US) | — |
| 6 | David H. Jones | Genomics Institute of the Nova… (US) | — |
| 7 | Hsien‐Po Chiu | Genomics Institute of the Nova… (US) | — |
| 8 | Xing Wang | Genomics Institute of the Nova… (US) | |
| 9 | Paula Patterson | Genomics Institute of the Nova… (US) | — |
| 10 | Huanfang Zhou | Genomics Institute of the Nova… (US) | — |
| 11 | Julie Vance | Genomics Institute of the Nova… (US) | — |
| 12 | Edward Nigoghossian | Genomics Institute of the Nova… (US) | — |
| 13 | Hung Tong | Genomics Institute of the Nova… (US) | — |
| 14 | Dylan Daniel | — | |
| 15 | William G. Mallet | — | — |
| 16 | Weijia Ou | Genomics Institute of the Nova… (US) | — |
| 17 | Tetsuo Uno | Genomics Institute of the Nova… (US) | — |
| 18 | Ansgar Brock | Genomics Institute of the Nova… (US) | |
| 19 | Scott A. Lesley | Genomics Institute of the Nova… (US) | |
| 20 | Bernhard H. Geierstanger Corresponding | Genomics Institute of the Nova… (US) |
Related Works
10Data: OpenAlex