Effect of subacute ibuprofen dosing on rectal mucosal prosta…
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- PMID https://pubmed.ncbi.nlm.nih.gov/10794478
- OpenAlex ID W2189137388
- Type Article
- Language EN
- Published 01 Apr 2000
- Volume 9 (4)
- Pages 351–6
- Source PubMed
- Publisher National Institutes of Health
- FWCI 1.49
- Countries 1
- Institutions 3
- Added 24 Jun 2016
- Updated 27 Oct 2026
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Effect of subacute ibuprofen dosing on rectal mucosal prostaglandin E2 levels in healthy subjects with a history of resected polyps.
Article 2000 EN
Nonsteroidal antiinflammatory drugs are among the most promising chemopreventive agents for colorectal cancer. Although the mechanism by which nonsteroidal antiinflammatory drugs exert such effects remains to be further characterized, their best known pharmacological effect is inhibition of prostaglandin synthetase, which leads to decreases in tissue prostaglandin levels. We conducted a randomized…
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11
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1.49
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11 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | H.‐H. Sherry Chow | University of Arizona (US) University of Arizona Cancer C… (US) | |
| 2 | David L. Earnest | University of Arizona (US) | — |
| 3 | David L. Clark | University of Arizona (US) | — |
| 4 | Nancy Mason-Liddil | University of Arizona (US) | — |
| 5 | Cheryl B. Kramer | University of Arizona (US) | — |
| 6 | Janine G. Einspahr | — | — |
| 7 | José Guillen-Rodriguez | University of Arizona (US) | — |
| 8 | Denise J. Roe | — | |
| 9 | Winfred F. Malone | National Institutes of Health (US) | — |
| 10 | James A. Crowell | National Institutes of Health (US) | — |
| 11 | David Samuel Alberts | — | — |
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