Cardiovascular depressor responses to stimulation of substan…

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Cardiovascular depressor responses to stimulation of substantia nigra and ventral tegmental area

Article 1997 EN

Experiments were done in alpha-chloralose-anesthetized, paralyzed, and artificially ventilated rats to investigate the effect of L-glutamate (Glu) stimulation of the substantia nigra (SN) and ventral tegmental area (VTA) on arterial pressure (AP) and heart rate (HR). Glu stimulation of the SN pars compacta (SNC) elicited decreases in both mean AP (MAP; -18.9 +/- 1.3 mmHg; n = 52) and HR (-26.1 +/-…

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1 Gilbert J. Kirouac Western University (CA)
2 John Ciriello Western University (CA)

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