Decrease in Number of Somatostatin Receptors in Rat Brain Af…

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1988
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Decrease in Number of Somatostatin Receptors in Rat Brain After Adrenalectomy: Normalization After Glucocorticoid Replacement*

Article 1988 EN

The effects of adrenalectomy on somatostatin (SS) concentration and specific binding in cerebral cortex, hippocampus, striatum, and hypothalamus were examined using [125I-Tyr11]SS as the binding ligand. Adrenalectomy did not affect the concentration of SS-like immunoreactivity in the brain areas studied. Nevertheless, the number of SS receptors was significantly decreased in membrane preparations…

18

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28

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3

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0.67

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1 MARIA NELLY RODRIGUEZ Universidad de Alcalá (ES) Hospital Universitario de La P… (ES) —
2 Antonio Gómez-Pan Universidad de Alcalá (ES) Hospital Universitario de La P… (ES) —
3 E. Arilla Universidad de Alcalá (ES) Hospital Universitario de La P… (ES)

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