Effect of acute exercise on glycogen synthase in muscle from…

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Effect of acute exercise on glycogen synthase in muscle from obese and diabetic subjects

Article 2012 EN Green

Insulin stimulates glycogen synthase (GS) through dephosphorylation of serine residues, and this effect is impaired in skeletal muscle from insulin-resistant [obese and type 2 diabetic (T2DM)] subjects. Exercise also increases GS activity, yet it is not known whether the ability of exercise to affect GS is impaired in insulin-resistant subjects. The objective of this study was to examine the effec…

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7 authors
#AuthorInstitutionsORCID
1 Jørgen Jensen National Institute of Occupati… (NO) Norwegian School of Sport Scie… (NO)
2 Puntip Tantiwong The University of Texas at San… (US) Texas Diabetes Institute (US) —
3 Jorid T. Stuenæs National Institute of Occupati… (NO) —
4 Marjorie Molina‐Carrión The University of Texas at San… (US) Texas Diabetes Institute (US) —
5 Ralph Anthony DeFronzo The University of Texas at San… (US) Texas Diabetes Institute (US)
6 Kei Sakamoto University of Dundee (GB) MRC Protein Phosphorylation an… (GB) +1
7 Nicolas Musi Corresponding The University of Texas at San… (US) Texas Diabetes Institute (US) +1

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