Prefrontal Cortex Lesions Augment the Location-related Firing Properties of Area TE/Perirhinal Cortex Neurons in a Working Memory Task

It has previously been proposed that prefrontal cortex may have some role in keeping temporal cortex-based representations "on-line" during a working memory task. To test this hypothesis, the effects of electrolytic prefrontal cortex lesions on the firing of area TE and perirhinal cortex (PRC) neurons were examined while rats performed a delayed non-match to position task in the T-maze. The behavi…