Insulin and Insulin Receptor Uptake into Rat Liver: Chloroqu…
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- DOI 10.2337/diab.34.10.1025
- PMID https://pubmed.ncbi.nlm.nih.gov/3899805
- OpenAlex ID W2148081393
- Type Article
- Language EN
- Published 01 Oct 1985
- Volume 34 (10)
- Pages 1025–1030
- Source Diabetes
- Publisher American Diabetes Association
- FWCI 1.33
- Countries 1
- Institutions 2
- Added 10 Oct 2025
- Updated 12 Oct 2026
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Insulin and Insulin Receptor Uptake into Rat Liver: Chloroquine Action on Receptor Recycling
Article 1985 EN
In the present study, the effect of chloroquine on both insulin and receptor distribution was examined in vivo. Insulin injection (25 nmol/100 g body wt) caused a marked accumulation of both insulin and its receptor in purified hepatic Golgi fractions by 15 min postinjection. Percoll fractionation of parent Golgi fractions resolved two endocytic components of low (rho = 1.040-1.050) and high (rho…
29
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26
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5
Authors
1.33
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1 SDGsAuthors & Affiliations
5 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Masood N. Khan | Royal Victoria Hospital (CA) McGill University (CA) | — |
| 2 | Sylvine Savoie | Royal Victoria Hospital (CA) McGill University (CA) | — |
| 3 | RAHAT J. KHAN | Royal Victoria Hospital (CA) McGill University (CA) | — |
| 4 | John J.M. Bergeron | Royal Victoria Hospital (CA) McGill University (CA) | |
| 5 | Barry I. Posner | Royal Victoria Hospital (CA) McGill University (CA) | — |
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