Somatostatin Inhibition of Growth Hormone Secretion by Somat…

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1989
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Somatostatin Inhibition of Growth Hormone Secretion by Somatotropes from Male, Female, and Androgen Receptor-Deficient Rats: Evidence for Differing Sensitivities*

Article 1989 EN

To investigate the role of somatostatin (SRIF) in regulating sexually dimorphic GH secretion, we used a reverse hemolytic plaque assay and acutely dispersed somatotropes from age-matched normal male, normal female, and androgen receptor-deficient, testicular feminized (Tfm) rats. Hemolytic plaques were developed after a 90-min incubation in the presence of GH antiserum, 10 nM GH-releasing hormone…

18

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34

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5

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1.36

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5 authors
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1 James R. Kerrigan University of Virginia Health … (US) Institut de pharmacologie de S… (CA) +3 —
2 PAUL M. MARTHA University of Virginia Health … (US) Institut de pharmacologie de S… (CA) +3 —
3 Richard J. Krieg University of Virginia Health … (US) Institut de pharmacologie de S… (CA) +3 —
4 Alan David Rogol University of Virginia Health … (US) Institut de pharmacologie de S… (CA) +3
5 William S. Evans University of Virginia Health … (US) Institut de pharmacologie de S… (CA) +3

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