Effect of Estrogen versus Testosterone on Circulating Osteop…
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- DOI 10.1210/jc.87.4.1550
- PMID https://pubmed.ncbi.nlm.nih.gov/11932280
- OpenAlex ID W2124998345
- Type Article
- Language EN
- Published 01 Apr 2002
- Volume 87 (4)
- Pages 1550–1554
- Source The Journal of Clinical Endocrinology & …
- Publisher Oxford University Press
- FWCI 6.80
- Countries 1
- Institutions 2
- Added 24 Jun 2016
- Updated 16 Oct 2026
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Effect of Estrogen versus Testosterone on Circulating Osteoprotegerin and Other Cytokine Levels in Normal Elderly Men
Article 2002 EN
Recent studies have shown that estrogen (E) likely plays a dominant role in inhibiting bone resorption in normal elderly men. Because both E and T inhibit osteoclast development and activity, stimulate osteoclast apoptosis, and inhibit osteoblast production of IL-6, it is unclear why T is less potent than E in inhibiting bone resorption in vivo. Osteoprotegerin (OPG) binds to and inactivates RANKL…
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1 SDGsAuthors & Affiliations
4 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Sundeep Khosla Corresponding | Mayo Clinic (US) | |
| 2 | Elizabeth J. Atkinson | Mayo Clinic (US) | |
| 3 | Colin Robert Dunstan | Amgen (United States) (US) | |
| 4 | W. Michael O’Fallon | Mayo Clinic (US) | — |
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