Bosentan does not improve pulmonary hypertension and lung re…

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2010
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  • DOI 10.1183/09031936.00053710
  • PMID https://pubmed.ncbi.nlm.nih.gov/20595149
  • OpenAlex ID W2123781441
  • Type Article
  • Language EN
  • Published 01 Jul 2010
  • Volume 37 (3)
  • Pages 578–586
  • Source European Respiratory Journal
  • Publisher European Respiratory Society
  • FWCI 1.86
  • Countries 1
  • Institutions 2
  • Added 24 Jun 2016
  • Updated 31 Oct 2026
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Bosentan does not improve pulmonary hypertension and lung remodeling in heart failure

Article 2010 EN Bronze

Pulmonary hypertension (PH) and right ventricular (RV) dysfunction associated with heart failure (HF) carry a poor prognosis. Although endothelin receptor antagonists (ERAs) demonstrated benefits in pulmonary arterial hypertension, their efficacy in PH associated with HF was not specifically evaluated. 2 weeks after myocardial infarction (MI) rats received bosentan (100 or 200 mg·kg(-1)·day(-1)) o…

23

Citations

40

References

4

Authors

1.86

FWCI

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1 SDGs
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4 authors
#AuthorInstitutionsORCID
1 B.H. Jiang Montreal Heart Institute (CA) Université de Montréal (CA) —
2 Jean‐Claude Tardif Montreal Heart Institute (CA) Université de Montréal (CA)
3 Yanfen Shi Montreal Heart Institute (CA) Université de Montréal (CA)
4 Jocelyn Dupuis Montreal Heart Institute (CA) Université de Montréal (CA)
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