Pressor effects of circulating endothelin are limited by its…
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- DOI 10.1073/pnas.85.24.9797
- PMID https://pubmed.ncbi.nlm.nih.gov/3059352
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/282868
- OpenAlex ID W2104840130
- Type Article
- Language EN
- Published 01 Dec 1988
- Volume 85 (24)
- Pages 9797–9800
- Source Proceedings of the National Academy of S…
- Publisher National Academy of Sciences
- FWCI 59.85
- Countries 1
- Institutions 3
- Added 24 Jun 2016
- Updated 28 Oct 2026
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Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.
Article 1988 EN Green
Endothelin releases prostacyclin and thromboxane A2 from guinea pig or rat isolated lungs and endothelium-derived relaxing factor in the perfused mesentery of the rat. Endothelin is also substantially removed by the pulmonary circulation of the rat in vitro and in vivo and by guinea pig lungs in vitro. In the rat, the effects of endothelin on the blood pressure vary from pressor (in pithed rats) t…
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59.85
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7 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Gilberto De Nucci | St Bartholomew's Hospital (GB) Queen Mary University of Londo… (GB) +1 | |
| 2 | R Thomas | St Bartholomew's Hospital (GB) Queen Mary University of Londo… (GB) +1 | — |
| 3 | Pedro D’Orléans-Juste | St Bartholomew's Hospital (GB) Queen Mary University of Londo… (GB) +1 | |
| 4 | Edson Antunes | St Bartholomew's Hospital (GB) Queen Mary University of Londo… (GB) +1 | |
| 5 | Claire E. Walder | St Bartholomew's Hospital (GB) Queen Mary University of Londo… (GB) +1 | — |
| 6 | Timothy David Warner | St Bartholomew's Hospital (GB) Queen Mary University of Londo… (GB) +1 | |
| 7 | John Robert Vane | St Bartholomew's Hospital (GB) Queen Mary University of Londo… (GB) +1 | — |
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