Leukotriene constriction of mouse pial arterioles in vivo is…
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- DOI 10.1161/01.str.21.11.1618
- PMID https://pubmed.ncbi.nlm.nih.gov/2173172
- OpenAlex ID W2103646290
- Type Article
- Language EN
- Published 01 Nov 1990
- Volume 21 (11)
- Pages 1618–1620
- Source Stroke
- Publisher Lippincott Williams & Wilkins
- FWCI 0.45
- Countries 1
- Institutions 2
- Added 24 Jun 2016
- Updated 27 Oct 2026
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Leukotriene constriction of mouse pial arterioles in vivo is endothelium-dependent and receptor-mediated.
Article 1990 EN Bronze
The diameters of pial arterioles of mice were monitored in vivo with an image-splitting technique and television microscopy. Concentrations of leukotriene C4 as low as 10(-7) M constricted the arterioles. The leukotriene C4-D4 receptor blocker ICI 198615 (10(-8) M) inhibited the response. Endothelial injury by helium-neon laser/Evans blue technique eliminated the constriction and unmasked a slight…
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0.45
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3 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | William I. Rosenblum | Virginia Commonwealth Universi… (US) Virginia Commonwealth Universi… (US) | |
| 2 | Guy H. Nelson | Virginia Commonwealth Universi… (US) Virginia Commonwealth Universi… (US) | — |
| 3 | H Nishimura | Virginia Commonwealth Universi… (US) Virginia Commonwealth Universi… (US) | — |
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