Amygdaloid Lesions: Differential Effect on Conditioned Stress and Immobilization-Induced Increases in Corticosterone and Renin Secretion

The purpose of this study was to examine the contribution of the central nucleus of the amygdala to the expression of stress-induced increase in corticosterone and renin secretion. Neurons in the central amygdaloid nucleus of male rats were destroyed by bilateral injections of ibotenic acid, a neurotoxin that destroys cells but leaves fibers of passage intact. Two weeks later, the rats were subjec…