ROCK Inhibition Facilitates the Generation of Human-Induced …

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2010
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  • DOI 10.1089/cell.2010.0051
  • PMID https://pubmed.ncbi.nlm.nih.gov/20858051
  • OpenAlex ID W2075757700
  • Type Article
  • Language EN
  • Published 21 Sep 2010
  • Volume 12 (6)
  • Pages 641–653
  • Source Cellular Reprogramming
  • Publisher Mary Ann Liebert, Inc.
  • FWCI 1.30
  • Countries 2
  • Institutions 2
  • Added 10 Oct 2025
  • Updated 21 Sep 2026
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ROCK Inhibition Facilitates the Generation of Human-Induced Pluripotent Stem Cells in a Defined, Feeder-, and Serum-Free System

Article 2010 EN Hybrid

Human-induced pluripotent stem cells (iPSCs) generated from human adult somatic cells through reprogramming hold great promises for future regenerative medicine. However, exposure of human iPSCs to animal feeder and serum in the process of their generation and maintenance imposes risk of transmitting animal pathogens to human subjects, thus hindering the potential therapeutic applications. Here, w…

51

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34

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9

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1.30

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9 authors
#AuthorInstitutionsORCID
1 Wing‐Hon Lai Queen Mary Hospital (CN) University of Hong Kong (HK)
2 Jenny Chung-Yee Ho Queen Mary Hospital (CN) University of Hong Kong (HK)
3 Yee-Ki Lee Queen Mary Hospital (CN) University of Hong Kong (HK) —
4 Kwong‐Man Ng Queen Mary Hospital (CN) University of Hong Kong (HK)
5 Ka‐Wing Au Queen Mary Hospital (CN) University of Hong Kong (HK)
6 Yau-Chi Chan Queen Mary Hospital (CN) University of Hong Kong (HK)
7 Chu‐Pak Lau Queen Mary Hospital (CN) University of Hong Kong (HK)
8 Hung‐Fat Tse Queen Mary Hospital (CN) University of Hong Kong (HK)
9 Chung‐Wah Siu Corresponding Queen Mary Hospital (CN) University of Hong Kong (HK)
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