Neuronal Estrogen Receptor-α Mediates Neuroprotection by 17β…

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Neuronal Estrogen Receptor-α Mediates Neuroprotection by 17β-Estradiol

Article 2009 EN Green

17beta-Estradiol (E(2)) was shown to exert neuroprotective effects both in in vitro and in vivo models of stroke. Although these effects of E(2) are known to require estrogen receptor-alpha (ER alpha), the cellular target of estrogen-mediated neuroprotection remains unknown. Using cell type-specific ER mutant mice in an in vivo model of stroke, we specifically investigated the role of ER alpha in…

76

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36

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7

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4.07

FWCI

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7 authors
#AuthorInstitutionsORCID
1 Joachim Elzer German Cancer Research Center (DE) Ludwig Cancer Research (BE) +1 —
2 Sajjad Muhammad Heidelberg University (DE)
3 Tim M Wintermantel German Cancer Research Center (DE) Bayer (Germany) (DE) —
4 Anne Régnier‐Vigouroux Inserm (FR) German Cancer Research Center (DE)
5 Jochen Ludwig Heidelberg University (DE) —
6 Günther Schütz German Cancer Research Center (DE) —
7 Markus Schwaninger Corresponding Heidelberg University (DE)

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