Circulating Immune Complexes in the Serum in Systemic Lupus …

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433
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47
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1974
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  • DOI 10.1172/jci107765
  • PMID https://pubmed.ncbi.nlm.nih.gov/4847246
  • OpenAlex ID W2062192514
  • Type Article
  • Language EN
  • Published 01 Aug 1974
  • Volume 54 (2)
  • Pages 297–309
  • Source Journal of Clinical Investigation
  • Publisher American Society for Clinical Inves…
  • FWCI 37.38
  • Countries 1
  • Institutions 2
  • Added 10 Oct 2025
  • Updated 14 Oct 2026
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Circulating Immune Complexes in the Serum in Systemic Lupus Erythematosus and in Carriers of Hepatitis B Antigen QUANTITATION BY BINDING TO RADIOLABELED Clq

Article 1974 EN Bronze

A sensitive and reproducible procedure for the detection of soluble immune complexes in sera from patients with various immunopathological disorders is reported. Radiolabeled C1q is reacted with sera containing immune complexes. Separation of free from complex bound [(125)I]C1q is achieved by selective precipitation with polyethylene glycol (PEG). The method is based on both the large molecular si…

433

Citations

47

References

4

Authors

37.38

FWCI

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1 SDGs
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4 authors
#AuthorInstitutionsORCID
1 Urs E. Nydegger University of Geneva (CH) World Health Organization (CH)
2 Paul Henri Lambert University of Geneva (CH) World Health Organization (CH) —
3 Heidi Gerber University of Geneva (CH) World Health Organization (CH) —
4 Peter A. Miescher — —
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