Glucocorticoids Provoke a Shift from α2‐ to α1‐Adrenorecepto…

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Glucocorticoids Provoke a Shift from α2‐ to α1‐Adrenoreceptor Activities in Cultured Hypothalamic Slices Leading to Opposite Noradrenaline Effect on Corticotropin‐Releasing Hormone Release

Article 1998 EN

We have shown previously that noradrenaline (NA) stimulated or inhibited the release of corticotropin-releasing hormone (CRH) according to the availability of adrenal steroids. The aim of the present work was to examine whether the changes in the NA modulation of CRH release from hypothalamic neurons result from a steroid-induced plasticity of the adrenergic transduction pathways. From anterior hy…

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7 authors
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1 Emmanuelle Feuvrier Centre National de la Recherch… (FR) Université Montpellier 2 (FR) —
2 Magali Aubert Centre National de la Recherch… (FR) —
3 Anne-Laure Mausset-Bonnefont Centre National de la Recherch… (FR)
4 Gérard Alonso Inserm (FR) Université Montpellier 2 (FR) —
5 Sylvie Gaillet Centre National de la Recherch… (FR)
6 Francis Malaval Centre National de la Recherch… (FR) —
7 ALAIN SZAFARCZYK Centre National de la Recherch… (FR) —

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