Activation and Multiple‐Site Phosphorylation of Tyrosine Hyd…

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Activation and Multiple‐Site Phosphorylation of Tyrosine Hydroxylase in Perfused Rat Adrenal Glands

Article 1992 EN

Tryptic digestion of tyrosine hydroxylase (TH) isolated from rat adrenal glands labeled with 32Pi produced five phosphopeptides. Based on the correspondence of these phosphopeptides with those identified in TH from rat pheochromocytoma cells, four phosphorylation sites (Ser8, Ser19, Ser31, and Ser40) were inferred. Field stimulation of the splanchnic nerves at either 1 or 10 Hz (300 pulses) increa…

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1 John W. Haycock Corresponding Louisiana State University (US) University Medical Center New … (US) +1
2 Arun R. Wakade Wayne State University (US) —

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