Increased expression of vascular angiotensin II type 1A rece…

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Increased expression of vascular angiotensin II type 1A receptor gene in glucocorticoid-induced hypertension

Article 1994 EN

OBJECTIVES: We recently demonstrated that glucocorticoid increases the number of angiotensin II type 1 (AT1) receptors and their gene expression in cultured vascular smooth muscle cells. To clarify whether this mechanism participates in glucocorticoid-induced hypertension, we investigated the effect of dexamethasone on the modulation of vascular AT1 receptor messenger RNA (mRNA) expression in rats…

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6

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6 authors
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1 Atsuhisa Sato Keio University (JP) —
2 Hiromichi Suzuki Keio University (JP)
3 Yuichi Nakazato Keio University (JP) —
4 Hirotaka Shibata Keio University (JP)
5 Tadashi Inagami Keio University (JP) —
6 Takao Saruta Keio University (JP) —

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