Endothelin-1 Induces an Endothelin-A-Receptor-Dependent and …
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- DOI 10.1097/00005344-200036001-00071
- PMID https://pubmed.ncbi.nlm.nih.gov/11078387
- OpenAlex ID W2040136656
- Type Article
- Language EN
- Published 01 Jan 2000
- Volume 36 (Supplement 1)
- Pages S241–S243
- Source Journal of Cardiovascular Pharmacology
- Publisher Lippincott Williams & Wilkins
- Countries 1
- Institutions 2
- Added 10 Oct 2025
- Updated 12 Oct 2026
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Endothelin-1 Induces an Endothelin-A-Receptor-Dependent and L-NAME-Sensitive Vasoconstriction in the Isolated Perfused Guinea-Pig Kidney
Article 2000 EN
We have previously reported a significant contribution of ET(A)- and ET(B)-receptors in the eicosanoid-releasing properties of endothelin-1 (ET-1) in the guinea-pig perfused lung. More recently, it was found that intravenously administered ET-1 in the guinea-pig triggers the release of hypotensive and bronchoconstrictive eicosanoids which is strongly modulated by endogenous nitric oxide. In this s…
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2 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Martine Duval | Université de Sherbrooke (CA) Institut de pharmacologie de S… (CA) | |
| 2 | Pedro D’Orléans-Juste Corresponding | Université de Sherbrooke (CA) Institut de pharmacologie de S… (CA) |
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