High Ornithine Decarboxylase Activity and Polyamine Levels i…
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- DOI 10.1097/00000658-198607000-00013
- PMID https://pubmed.ncbi.nlm.nih.gov/3729588
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/1251228
- OpenAlex ID W2032773367
- Type Article
- Language EN
- Published 01 Jul 1986
- Volume 204 (1)
- Pages 89–93
- Source Annals of Surgery
- Publisher Lippincott Williams & Wilkins
- FWCI 3.03
- Countries 1
- Institutions 2
- Added 24 Jun 2016
- Updated 28 Oct 2026
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High Ornithine Decarboxylase Activity and Polyamine Levels in Human Colorectal Neoplasia
Article 1986 EN Green
Polyamines are required for cell proliferation, and ornithine decarboxylase (ODC) is the first and probably rate-limiting enzyme in their synthesis. Tissue containing colonic or rectal adenocarcinomas (N = 34) or polyps (N = 6) and noninvolved paired colonic mucosa were obtained from fresh surgical specimens. ODC activity was elevated (mean: 320%) in both the cancer and polyps. In noninvolved colo…
111
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3.03
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1 SDGsAuthors & Affiliations
3 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Glenn M. LaMuraglia | Harvard University (US) Massachusetts General Hospital (US) | |
| 2 | FRANÇOIS LACAINE | Harvard University (US) Massachusetts General Hospital (US) | — |
| 3 | Ronald A. Malt | Harvard University (US) Massachusetts General Hospital (US) | — |
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