Assay of human stem cells by repopulation of NOD/SCID mice
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- DOI 10.1002/stem.5530150826
- PMID https://pubmed.ncbi.nlm.nih.gov/9368342
- OpenAlex ID W2032594449
- Type Review
- Language EN
- Published 01 Apr 1997
- Volume 15 (S2)
- Pages 199–207
- Source Stem Cells
- Publisher Oxford University Press
- FWCI 1.99
- Countries 1
- Institutions 2
- Added 24 Jun 2016
- Updated 27 Oct 2026
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Assay of human stem cells by repopulation of NOD/SCID mice
Review 1997 EN
The only conclusive method to assay stem cells is to follow their ability to repopulate conditioned recipients, making it difficult to study human stem cells. The development of systems to transplant human hematopoietic cells into immune-deficient mice lays the foundation for such an experimental repopulation assay for primitive human cells. Cell purification and gene marking studies have shown th…
180
Citations
36
References
5
Authors
1.99
FWCI
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
5 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | John Edgar Dick | University of Toronto (CA) Hospital for Sick Children (CA) | |
| 2 | Mickie Bhatia | University of Toronto (CA) Hospital for Sick Children (CA) | |
| 3 | Olga I. Gan | University of Toronto (CA) Hospital for Sick Children (CA) | — |
| 4 | Ursula Kapp | University of Toronto (CA) Hospital for Sick Children (CA) | — |
| 5 | Jean C. Y. Wang | University of Toronto (CA) Hospital for Sick Children (CA) |
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